EurekAlert! - Cancer

The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.http://www.eurekalert.org en-usCopyright 2012 by the American Association for the Advancement of ScienceTue, 06 Mar 2012 16:54:03 ESTEurekAlert!http://www.eurekalert.org/images/logo.gifhttp://www.eurekalert.org The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.60webmaster@eurekalert.org (EurekAlert!)(<i>University of Colorado Denver</i>) NCI SPECS grant, coordinated by Fred R. Hirsch at the University of Colorado Cancer Center, will bring nine institutions together to search for biomarkers and targeted treatments for squamous cell lung cancer.http://www.eurekalert.org/pub_releases/2012-03/uocd-ccc030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uocd-ccc030612.php(<i>Purdue University</i>) Purdue University researchers have created a new imaging technology that reveals subtle changes in breast tissue, representing a potential tool to determine a woman's risk of developing breast cancer and to study ways of preventing the disease.http://www.eurekalert.org/pub_releases/2012-03/pu-sir030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/pu-sir030612.php(<i>WHITECOAT STRATEGIES, LLC</i>) About 20 percent of breast cancer patients develop lymphedema, an accumulation of lymphatic fluid that causes swelling, often in the limbs. The disease may result in a disfiguring and painful condition. Attempts to treat lymphedema with lymph node transplant surgery offer modest results. Dr. Alitalo's and his team discovered that infusion of VEGF-C at the surgery site may significantly increase successful transplant. The Lymphatic Research Foundation awards Dr. Alitalo the 2012 Lymphatic Research Leadership Award.http://www.eurekalert.org/pub_releases/2012-03/iofb-kaw030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/iofb-kaw030612.php(<i>Scripps Research Institute</i>) A pair of Scripps Research Institute scientists, one a cancer biologist and the other a chemist, has been awarded $3.85 million from the National Institutes of Health (NIH) to develop a new generation of broad spectrum anti-cancer therapeutics, including breast cancer and lymphoma.http://www.eurekalert.org/pub_releases/2012-03/sri-sfs030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/sri-sfs030612.php(<i>Northwestern University</i>) Northwestern University scientists have developed a powerful analytical method that they have used to direct stem cell differentiation. Out of millions of possibilities, they rapidly identified the chemical and physical structures that can cue stem cells to become osteocytes, cells found in mature bone. Researchers can use the method, called nanocombinatorics, to build enormous libraries of physical structures varying in size from a few nanometers to many micrometers for addressing problems within and outside biology.http://www.eurekalert.org/pub_releases/2012-03/nu-isc030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/nu-isc030612.php(<i>Max-Planck-Gesellschaft</i>) Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now discovered that they can prevent the formation of metastases by blocking the receptor protein Plexin B1.http://www.eurekalert.org/pub_releases/2012-03/m-rdp030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/m-rdp030612.php(<i>H. Lee Moffitt Cancer Center & Research Institute</i>) Researchers at Moffitt Cancer Center and colleagues from 11 other institutions in the United States and the United Kingdom have used two genome-wide association studies -- one from the US and one from the UK -- to detect a novel set of genes found to be associated with epithelial ovarian cancer patient survival. The discovery could open the door to new therapies for treating epithelial ovarian cancer, the most lethal kind of gynecologic malignancy.http://www.eurekalert.org/pub_releases/2012-03/hlmc-rfp030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/hlmc-rfp030612.php(<i>Damon Runyon Cancer Research Foundation</i>) Today, the Damon Runyon Cancer Research Foundation held its first Accelerating Cancer Cures Research Symposium, focused on rebuilding the ranks of physician-scientists specially trained to translate laboratory discoveries into new cancer therapies. The event, held at Pfizer Inc headquarters, brought together academic scientists and other leading pharmaceutical companies, including Eli Lilly and Company, Celgene, Genentech, Merck, and Millennium: The Takeda Oncology Company.http://www.eurekalert.org/pub_releases/2012-03/drcr-ilj030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/drcr-ilj030612.php(<i>North Carolina State University</i>) Modeling biological systems can provide key insights for scientists and medical researchers, but periodic cycles that repeat themselves -- so-called oscillatory systems -- pose some key challenges. Researchers at North Carolina State University have developed a new method for estimating the parameters used in such models -- which may advance modeling in research areas ranging from cancer to fertility.http://www.eurekalert.org/pub_releases/2012-03/ncsu-nmf030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/ncsu-nmf030612.php(<i>IDIBELL-Bellvitge Biomedical Research Institute</i>) A study, led by the researcher at the Bellvitge Biomedical Research Institute, Manel Esteller, published in the Journal of Pathology, had identified a mechanism that explains how cancer cells escape from its original site to the lymph nodes. Investigations have uncovered that metastatic tumor cells that grow in the lymph nodes of patients with melanoma and head and neck tumors lose the activity of a protein called cadherin-11.http://www.eurekalert.org/pub_releases/2012-03/ibri-tlo030612.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/ibri-tlo030612.php(<i>Centro Nacional de Investigaciones Oncologicas (CNIO)</i>) Researchers from the Spanish National Cancer Research Centre working with mice have revealed that one of the main genes protecting against cancer brings two additional health benefits by boosting longevity and combating obesity. Mice carrying extra copies of the study gene eat more than normal, but are thinner -- a novel and entirely unexpected outcome.http://www.eurekalert.org/pub_releases/2012-03/cndi-csd030512.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/cndi-csd030512.php(<i>Journal of the National Cancer Institute</i>) Two studies published March 6 in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the usefulness of CYP2D6 testing for deciding whether or not a patient should receive adjuvant tamoxifen for treatment of early-stage breast cancer.http://www.eurekalert.org/pub_releases/2012-03/jotn-sst030512.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/jotn-sst030512.php(<i>Journal of the National Cancer Institute</i>) The first therapeutic cancer vaccine has now been approved by the FDA, and a diverse range of therapeutic cancer vaccines directed against a spectrum of tumor-associated antigens are currently being evaluated in clinical trials, according to a review published March 6 in the Journal of the National Cancer Institute.http://www.eurekalert.org/pub_releases/2012-03/jotn-tco030512.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/jotn-tco030512.php(<i>University of Rochester Medical Center</i>) The number of cancer survivors in the United States has tripled since 1971 and yet gains in survival have come at the price of second malignancies and cardiovascular disease, according to a long-awaited report by a national scientific committee chaired by Lois B. Travis, M.D., Sc.D., of the University of Rochester Medical Center.http://www.eurekalert.org/pub_releases/2012-03/uorm-rhu030512.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uorm-rhu030512.php(<i>University of California - Los Angeles Health Sciences</i>) Researchers at UCLA's Jonsson Comprehensive Cancer Center have uncovered how an advanced form of melanoma gets around an inhibitor, Zelboraf, which targets the mutated BRAF gene.http://www.eurekalert.org/pub_releases/2012-03/uoc--usu030212.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uoc--usu030212.php(<i>Cell Press</i>) In a perfect world, we could eat to our heart's content without sacrificing our health and good looks, and now it appears that maybe we can. Mice with an extra dose of a known anti-cancer gene lose weight even as their appetites grow. Not only that, but according to the report in the March issue of the Cell Press journal Cell Metabolism, the animals also live longer, and that isn't just because they aren't getting cancer, either.http://www.eurekalert.org/pub_releases/2012-03/cp-weg022912.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/cp-weg022912.php(<i>DOE/Brookhaven National Laboratory</i>) Scientists have deciphered molecular-level details of the complex choreography by which intricate cellular proteins recognize and bind to DNA to start the DNA replication process. The research may point to ways to block unwanted cell division.http://www.eurekalert.org/pub_releases/2012-03/dnl-srh022912.php Tue, 06 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/dnl-srh022912.php(<i>University of California - San Diego</i>) A team of scientists at the University of California, San Diego Moores Cancer Center has identified a novel protein expressed by breast cancer cells -- but not normal adult tissues -- that could provide a new target for future anti-cancer drugs and treatments.http://www.eurekalert.org/pub_releases/2012-03/uoc--edp030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uoc--edp030512.php(<i>Ohio State University Medical Center</i>) A new study provides evidence that immune cells called T lymphocytes, or T cells, can develop in human tonsils. The cells have been thought to develop only in the thymus, an organ of the immune system that sits on the heart. The findings could be important for improving stem-cell transplantation and for understanding the development of T-cell cancers and autoimmune diseases.http://www.eurekalert.org/pub_releases/2012-03/osum-tmt030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/osum-tmt030512.php(<i>University of Gothenburg</i>) Every day 18 Swedish women are diagnosed with breast cancer. Although there is a real need for support and information, many women struggle and get lost in the deluge of information. In a study of 227 women, researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have developed a web-based program to guide patients all the way from diagnosis to rehabilitation.http://www.eurekalert.org/pub_releases/2012-03/uog-wsh030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uog-wsh030512.php(<i>University of Pennsylvania School of Medicine</i>) Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T cells. It is the first time a system for making an adaptable, engineered T-cell to attack specific tumor types has been proposed, depending on which abnormal proteins, called antigens, are expressed by individual patients' tumor cells.http://www.eurekalert.org/pub_releases/2012-03/uops-nup030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uops-nup030512.php(<i>Deane, Smith & Partners</i>) Chinese Minister of Health, Dr. Zhu Chen, will hold talks tomorrow, March 6, with leading cancer researchers from across the US and China with the goal of developing a stronger platform for broader Sino-US research collaboration and creating deeper ties to fast-track cancer research.http://www.eurekalert.org/pub_releases/2012-03/dsm-cmo030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/dsm-cmo030512.php(<i>University of Zurich</i>) Researchers from the University of Zurich have found a cellular brake that protects cancer cells from chemotherapy -- and they demonstrate which medication can be used to render it inoperative. Their study published in the journal Natural Structural and Molecular Biology provides the molecular basis for promising therapeutic advances.http://www.eurekalert.org/pub_releases/2012-03/uoz-hcb030512.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/uoz-hcb030512.php(<i>The Translational Genomics Research Institute</i>) Two research scientists from the Translational Genomics Research Institute will discuss the potential of ?Personalize Medicine? at a forum organized as part of the Arizona SciTech Festival. The free public forum, presented by public radio station KJZZ and Rio Salado College, is scheduled from 7-9 pm March 8 at the Rio Salado Conference Center, 2323 W. 14th Street, Tempe, Ariz.http://www.eurekalert.org/pub_releases/2012-03/ttgr-trs030212.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/ttgr-trs030212.php(<i>Yale University</i>) Even though a large clinical study demonstrated that radiation has limited benefit in treating breast cancer in some older women, there was little change in the use of radiation among older women in the Medicare program, Yale School of Medicine researchers report in the March Journal of Clinical Oncology.http://www.eurekalert.org/pub_releases/2012-03/yu-rsu030112.php Mon, 05 Mar 2012 00:00:00 ESThttp://www.eurekalert.org/pub_releases/2012-03/yu-rsu030112.php

Source: http://www.eurekalert.org/rss/cancer.xml

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